MR imaging of an arachidonic acid-induced mouse model of thrombosis using an activated platelets-targeted paramagnetic contrast agent
نویسندگان
چکیده
A. Klink, E. Lancelot, S. Ballet, W. Gonzalez, C. Medina, C. Corot, J-E. Fabre, W. J. Mulder, Z. Mallat, and Z. A. Fayad Translational and Molecular Imaging Institute, Mount Sinai School Of Medicine, New York, NY, United States, INSERM U689, Paris, France, Research Division, Guerbet, France, Atherothrombosis Laboratory, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Strasbourg, France
منابع مشابه
Magnetic resonance molecular imaging of thrombosis in an arachidonic acid mouse model using an activated platelet targeted probe.
OBJECTIVE Atherosclerotic plaque rupture leads to acute thrombus formation and may trigger serious clinical events such as myocardial infarction or stroke. Therefore, it would be valuable to identify atherothrombosis and vulnerable plaques before the onset of such clinical events. We sought to determine whether the noninvasive in vivo visualization of activated platelets was effective when usin...
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تاریخ انتشار 2008